storescas.blogg.se

(See nomogram.)Īssistance available from a regional poison center at 80 or an assistance line for acetaminophen overdosage at 80.

Use plasma or serum acetaminophen concentrations in conjunction with a nomogram to estimate potential for hepatotoxicity and necessity of acetylcysteine therapy.įull course of acetylcysteine therapy indicated if initial plasma or serum acetaminophen concentrations fall on or above the dashed line on the nomogram. May be appropriate to obtain an additional sample at 4–6 hours after initial sample if extended-release acetaminophen preparation was ingested. Acetylcysteine Dosage and Administration Generalĭetermine plasma or serum acetaminophen concentrations as soon as possible (but no sooner than 4 hours) after ingestion. Used during anesthesia and in the preparation of patients for bronchograms, bronchospirometry, bronchial wedge catheterization, and other diagnostic bronchial studies. Mucolytic UsesĪdjunctive treatment for patients with abnormal, viscid, or inspissated mucous secretions associated with conditions such as acute and chronic bronchopulmonary disorders (e.g., pneumonia, bronchitis, emphysema, tracheobronchitis, chronic asthmatic bronchitis, tuberculosis, bronchiectasis, primary amyloidosis of the lung) atelectasis caused by mucus obstruction pulmonary complications of cystic fibrosis pulmonary complications of thoracic and cardiovascular surgery and post-traumatic chest conditions. Efficacy for this indication not established additional study needed. Has been used to prevent radiographic contrast media-induced nephropathy †. Prevention of Nephropathy Associated with Radiographic Contrast Media Optimal if given within 8 hours of acetaminophen ingestion may be effective when given ≥24 hours after ingestion. Uses for Acetylcysteine Antidote for Acetaminophen Overdosage Written by ASHP.Īntidote for acetaminophen overdosage mucolytic agent and sulfhydryl donor.